What does HGNC stand for?
HUGO Gene Nomenclature Committee
| Content | |
|---|---|
| Description | HGNC is responsible for approving unique symbols and names for human loci, including protein coding genes, RNA genes and pseudogenes, to allow unambiguous scientific communication. |
| Data types captured | Gene nomenclature |
| Organisms | Human |
| Contact |
What is an HGNC ID?
HGNC ID. A unique ID provided by the HGNC for each gene with an approved symbol. IDs are of the format HGNC:n, where n is a unique number. HGNC IDs remain stable even if a name or symbol changes.
How do you reference HGNC?
To cite data within the database use the following format: HGNC Database, HUGO Gene Nomenclature Committee (HGNC), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom www.genenames.org.
How are human genes named?
How do genes get their names? When a scientist discovers a new human gene, he or she submits a proposed name to the Human Gene Nomenclature Committee (HGNC), an international panel of researchers with exclusive authority over this area. Guidelines were established in 1979 by the HGNC and have been updated periodically.
How many genes do humans have?
In humans, genes vary in size from a few hundred DNA bases to more than 2 million bases. An international research effort called the Human Genome Project, which worked to determine the sequence of the human genome and identify the genes that it contains, estimated that humans have between 20,000 and 25,000 genes.
Are human gene names italicized?
Gene names that are written out in full are not italicized (e.g., insulin-like growth factor 1). Genotype designations should be italicized, whereas phenotype designations should not be italicized.
What is Official gene symbol?
Gene symbols generally are italicised, with all letters in uppercase (e.g., NLGN1, for neuroligin1). Protein designations are the same as the gene symbol, but are not italicised; all letters are in uppercase (NLGN1). mRNAs and cDNAs use the same formatting conventions as the gene symbol.
Do we Italicise gene names?
The scientific names of species are italicized. The genus name is always capitalized and is written first; the specific epithet follows the genus name and is not capitalized. There is no exception to this.
Are humans 99.9 percent the same?
All human beings are 99.9 percent identical in their genetic makeup. Differences in the remaining 0.1 percent hold important clues about the causes of diseases.
What is the symbol for DNA?
Nucleotide symbols
| Nucleotide symbol | Full Name |
|---|---|
| B | Guanine / Thymine / Cytosine |
| D | Guanine / Adenine / Thymine |
| H | Adenine / Cytosine / Thymine |
| V | Guanine / Cytosine / Adenine |